发表SCI论文(#第一作者, *通讯作者)
1. Ge C#, Wang Y#, Feng Y#, Wang S, Zhang K, Xu X, Zhang Z, Zhao Y, Wang Y, Gao L, Dai F*, Xie S*, Wang C*. Suppression of oxidative phosphorylation and IDH2 sensitizes colorectal cancer to a naphthalimide derivative and mitoxantrone. Cancer Lett. 2021, (28) 519:30-45.
2. Dai F, Li Q, Wang Y*, Ge C, Feng C, Xie S*, He H, Xu X, Wang C*. Design, synthesis, and biological evaluation of mitochondria-targeted flavone-naphthalimide-polyamine conjugates with antimetastatic activity. J Med Chem. 2017,60(5):2071-2083.
3. Li J, Tian R, Ge C, Chen Y, Liu X, Wang Y*, Yang Y, Luo W, Dai F*, Wang S, Chen S, Xie S; Wang C*. Discovery of the Polyamine Conjugate with Benzo[cd]indol-2(1 H)-one as a Lysosome-Targeted Antimetastatic Agent. 2018, J Med Chem, 61(15): 6814-6829.
4. Gao L#, Feng Y#, Ge C, Xu X, Wang S, Li X, Zhang K, Wang C, Dai F*, Xie S*. Identification of molecular anti-metastasis mechanisms of lycorine in colorectal cancer by RNA-seq analysis. Phytomedicine. 2021,85:153530.
5. Dai F#*, Gao L#, Zhao Y, Wang C, Xie S*. Farrerol inhibited angiogenesis through Akt/mTOR, Erk and Jak2/Stat3 signal pathway. Phytomedicine. 2016, 23(7):686-93.
6. Wang S#, Xu X#, Che D, Fan R, Gao M, Cao Y, Ge C, Feng Y, Li J, Xie S, Wang C, Dai F*, Gao L, Wang Y*. Reactive oxygen species mediate 6c-induced mitochondrial and lysosomal dysfunction, autophagic cell death, and DNA damage in hepatocellular carcinoma. Int J Mol Sci. 2021, 22(20):10987.
7. Li M, Wang Y, Ge C, Chang L, Wang C, Tian Z*, Wang S, Dai F*, Zhao L, Xie S*. Synthesis and biological evaluation of novel alkylated polyamine analogues as potentialanticancer agents. Eur J Med Chem. 2018, 143:1732-1743.
8. Fan R#, Wang S#, Wu Y#, Feng Y, Gao M, Cao Y, Ma X, Xie S, Wang C, Gao L*, Wang Y*, Dai F*. (2023) Activation of endoplasmic reticulum stress by harmine suppresses the growth of esophageal squamous cell carcinoma. Phytother Res. 2023, 37(10):4655-4673.
9. Gao L#, Ge CC#, Wang SZ, Xu XJ, Feng YL, Li XN, Wang CJ, Wang YX, Dai FJ *, Xie SQ*. The Role of p53-Mediated Signaling in the Therapeutic Response of Colorectal Cancer to 9F, a Spermine-Modified Naphthalene Diimide Derivative. Cancers (Basel). 2020, 12(3): E528.
10. Dai F, He H, Xu X, Chen S, Wang C, Feng C, Tian Z*, Dong H, Xie S*. Synthesis and biological evaluation of naphthalimide-polyamine conjugates modified by alkylation as anticancer agents through p53 pathway. Bioorg Chem. 2018, 77:16-24.
11. Xu X#, Wang S#, Chang Y, Ge C, Li X, Feng Y, Xie S, Wang C, Dai F*, Luo W*. Synthesis and biological evaluation of novel asymmetric naphthalene diimide derivatives as anticancer agents depending on ROS generation. Medchemcomm. 2018, 9(8):1377-1385.
12. Dai F#, Chen Y#, Li H, Wang J, Zhang T, Li J, Tong W, Liu M, Yi Z*. A novel synthetic small molecule YH-306 suppresses colorectal tumor growth and metastasis via FAK pathway. J Cell Mol Med. 2015, 19(2):383-95.
13. Ge C, Chang L, Zhao Y, Chang C, Xu X, He H, Wang Y*, Dai F*, Xie S* and Wang C. Design, Synthesis and Evaluation of Naphthalimide Derivatives as Potential Anticancer Agents for Hepatocellular Carcinoma. Molecules. 2017, 22(2), 342.
14. Dai F, Chen Y*, Song Y, Li H, Zhai D, Dong Y, Lai L, Zhang T, Li D, Pang X, Liu M*, Yi Z*. A natural small molecule harmine inhibits angiogenesis and suppresses tumour growth through activation of p53 in endothelial cells. PLoS One. 2012, 7(12):e52162.
15. Dai F, Cao Y, Zhu C, Li Y, Ma X, Wang S, Liu H, Xie X, Gao L*, Wang Y*, Wang C*. Design, Synthesis and Biological Evaluation of Naphthalimide-Polyamine Conjugate as a Potential Anti-Colorectal Cancer Agent. Chem Biodivers. 2024, e202401873.
16. Xu X#, Ge C#, Wang S, Gao L, Wang C, Dai F*, Wang Y*, Xie S*. Polyamine-modified naphthalimide derivative 9C inhibits colorectal cancer through ROS-mediated ER stress, migration and invasion. Toxicol In Vitro. 2024, 103:105974.
17. Dai F, Yu W, Song J, Li Q, Wang C*, Xie S*. Extracellular polyamines-induced proliferation and migration of cancer cells by ODC, SSAT, and Akt1-mediated pathway. Anticancer Drugs. 2017, 28(4):457-464.