河南大学医学院官方网站

齐义军

副教授、博士、硕导
齐义军

  齐义军,男(1972年),副教授,博士,硕士研究生导师,留学归国学者。主要从事食管癌变的分子机制及肿瘤标志物筛查与鉴定方面的研究,主持国家自然科学基金2项、教育部重点项目1项、河南省高等学校青年骨干教师资助1项,已发表40余篇论文和文摘,参编国际专著1项,其中SCI论文11篇,最高单篇引用次数达151次。

一、近年主持的主要科研项目

1.食管鳞癌中侯选抑癌蛋白14-3-3σ结合蛋白的蛋白质组研究(国家自然科学基金项目,30700366,2008-2010),17万,项目主持人。

2.食管鳞癌糖蛋白差异表达谱研究(国家自然科学基金面上项目,81072039,2011-2013),33万,项目主持人。

3.同一个体食管/贲门双源癌蛋白质组研究(国家自然科学基金项目,30670956,2007-2009),主要参与人。

4.细胞培养稳定同位素标记联用质谱定量研究食管鳞癌蛋白差异表达谱(教育部科学技术研究重点项目,211101),5万,项目主持人。

二、代表性论文

1.Qi YJ,Ward DG,Pang C,Wang QM,Wei W,Ma J,Zhang J,Lou Q,Shimwell NJ,Martin A,

Wong N,Chao WX,Wang M,Ma YF,Johnson PJ. Proteomic Profilingof N-linked Glycoproteins

Identifies ConA-binding Pro-cathepsin D as a Novel

Serum Biomarker for Hepatocellular Carcinoma.Proteomics.2013 Nov 20.

doi: 10.1002/pmic.201300226. [Epub ahead of print]

2.Hu YZ, Zhang J, Li S, Wang C, Chu L, Zhang Z, Ma Z, Wang M, Jiang Q, Liu G,Qi YJ,

Ma Y.The transcription activity of heat shock factor 4b is regulated by FGF2.

Int J Biochem Cell Biol, 2013, 45(2): 317-325

3.Yi-Jun Qi, Wei-Xia Chao, Jen-Fu Chiu.

An overview of esophageal squamous cell carcinoma proteomics. J Proteomics,

2012, 75(11): 3129-3137

4.Qi-Ming Wang,Yi-Jun Qi(Joint first authors),Qi Jiang,

Yuan-Fang Ma,

Li-Dong Wang. Relevanceof serum estradiol andestrogen

receptor beta

expression fro ahigh-incidence areaforesophageal

squamous cell

carcinomain China. Med Oncol. 2011; 28(1):188-193

5.Qi-Ming Wang, Ling Yuan,Yi-Jun Qi, Zhi-Yong Ma, Li-Dong Wang. Estrogenanalogues:

Promising target forprevention and treatment ofesophageal

squamouscell

carcinoma in high risk areas. Med Sci Monit. 2010; 16(7): HY12-22

6.Ward DG, Wei W, Buckels J, Taha AM, Hegab B, Taricotti L, Salih R,Qi YJ, Martin A,

Johnson PJ. Detection of pancreatic adenocarcinoma using circulating fragments of

fibrinogen. Eur J Gastroenterol Hepatol 2010; 22(11): 1358-1363

7.Y Mohri, T Mohri, W Wei,Y-J Qi, A Martin, C Miki,M

Kusunoki,

DG Ward and PJ Johnson.Identification of macrophge migration inhibitoryfactor

and humanneutrophilpeptides1-3 aspotentialbiomarkers

for gastric cancer. British

Journal of Cancer. 2009, 101: 295-302

8.Yi-Jun Qi, Qing-Yu He, Yuan-Fang Ma, Yao-Wu Du, Guang-Chao Liu, Yan-Jie Li,

GeorgeSW Tsao, Sai Ming Ngai, JenFu Chiu. Proteomic identificationof malignant

transformation-related proteins in esophageal squamous cell

carcinoma. Journal

of Cellular Biochemistry. 2008, 104: 1625-1635

9.Yijun Qi, Jen-Fu Chiu, Li-Dong Wang, Dora L. W. Kwong, Qing-Yu He. Comparative

proteomic analysis of esophageal squamous cell carcinoma.

Proteomics, 2005, 5: 2960-2971

四、著作

1.《药用医学基础概论》,编委,中国医药科技出版社,2007年5月第1版。ISBN: 978-7-5067-3725-8

2.《Proteomics-Human Diseases and Protein Functions》,

Publishedby InTech, 2012,

ISBN 978-953-307-832-8,Chapter 12 Proteomic study of

esophagealsquamous cell carcinoma.