男,1968年生,博士,副教授。
受教育经历 (Educational Experience)(从大学本科开始,按时间倒排序):
2005.3-2009.3 天津大学应用化学专业 博士研究生
2001.9-2004.6 河南中医学院中药专业 硕士研究生
工作经历(Professional Experience)(按时间倒排序):
2003. 7至今 河南大学药学院 副教授;
研究兴趣(Research Interests):1)药物合成;2) 小分子与生物大分子相互作用研究:
承担项目情况:
(1)河南省重点科技攻关项目,132102310026,芳香酰亚胺衍生物合成、生物活性, 2013/01-2015/12,5万元,已结题、主持
(2)中国博士后科学基金第四十九批项目,20110490991,萘酰亚胺衍生物合成及其抗肿瘤活性评价, 2011/05-2014/11,3万元,已结题,主持。
(3)河南省自然科学与基础前沿项目,112300410181、新型萘酰亚胺衍生物抗肿瘤活性及其作用机制研究,2011/01-2014/10,0 万元,已结题,主持
代表性论文(Publications)
第一作者论文
(1) Tian Zhiyong,Huang Yingying,Zhang Yan,Song Lina,Qiao Yan,Xu Xuejun,Wang Chaojie, Spectroscopic and molecular modeling methods to study the interaction between naphthalimide-polyamine conjugates and DNA, Journal of Photochemistry and Photobiology B-Biology,2016.5.01,158:1~159(SCI).
(2) Tian Zhi-Yong,Song Li-Na,Zhao Yuan,Zang Feng-Lei,Zhao Zhong-Hua,Chen Nan-Hao,Xu Xue-Jun,Wang Chao-Jie,Spectroscopic study on the Interaction between naphthalimide-polyamine conjugates and bovine serum albumin (BSA),Molecules,2015.9.01,20(9):16491~16523(SCI).
(3) Tian Zhiyong,Zang Fenglei,Luo Wen,Zhao Zhonghua,Wang Yuegiao,Xu Xuejun,Wang Chaojie, Spectroscopic study on the interaction between mononaphthalimide spermidine (MINS) and bovine serum albumin (BSA),Journal of Photochemistry and Photobiology B: Biology,2015.1.01,142:103~109(SCI).
(4) Tian, Zhiyong,Zhao Zhonghua,Zang Fenglei,Wang Yueqiao,Wang Chaojie, Spectroscopic study on the interaction between naphthalimide-polyamine conjugates and DNA,Journal of Photochemistry and Photobiology B-Biology,2014.9.5,138:202~210.
(5) Tian Zhi-Yong,Li Jing-Hua,Li Qian,Zang Feng-Lei,Zhao Zhong-Hua,Wang Chao-Jie, Study on the synthesis, biological activity and spectroscopy of naphthalimide-diamine conjugates,Molecules,2014.6.01,19(6):7646~7668(SCI).
(6) 田智勇,苏雷朋,谢松强,赵瑾,王超杰,萘酰亚胺-多胺缀合物的合成、生物活性和荧光光谱,有机化学,2013.2.01,(07):1514~1521(SCI).
(7) Tian Zhiyong,Zhao Luyao,Dong Huanyang,Zhang Yan, Zhang Yijuan,Ren Qianlei,Shao Shuangyu,Huang Yingying,Song Lina,Guo Tao,Xu Xuejun,Wang Chaojie, Study on the interaction of anthracenyl-methyl homospermidine conjugate (ANTMHspd) with DNA by spectroscopic methods,Journal of Photochemistry and Photobiology B: Biology,2017.03.02,169:27~34(SCI).