女,1978年生,河南省药品评审专家,副教授,药物分析、中药学学术型硕士导师,中药学专业型硕士导师
受教育经历 (Educational Experience)(从大学本科开始,按时间倒排序):
2004.9-2007.6:沈阳药科大学(博士研究生)
2001.9-2004.6:沈阳药科大学(硕士研究生)
1997.9-2001.6:沈阳药科大学(本科)
工作经历(Professional Experience)(按时间倒排序):
2011.11-2012.05,香港浸会大学理学院,博士后
2007.7-至今,河南大学,药学院,副教授;
研究兴趣(Research Interests)
以中药药效物质基础、质量标准及体内药物代谢动力学分析为研究方向;特色:结合药物代谢研究,深入探讨中药药效物质基础及药效、毒理机制。
承担项目情况(Financial Supports)(包括项目名称,批准号,金额,起止年月,基金来源,本人角色)
(1)具有神经基因毒性藜芦属甾体生物碱的构毒关系及机制研究,21102035, 25万,国家自然基金项目,2012-2014,主持。
(2)藜芦生物碱降压活性构效关系及减毒研究,162300410041,10万元,河南省自然科学基金,2017-2018,主持。
(3)河南省高等学校青年骨干教师培养计划项目,2016GGjs-031,4万元,,河南省教育厅,2017-2019,主持。
(4)具有神经基因毒性藜芦生物碱体内代谢产物的构毒关系及机制研究,xxjc20140018,
27万元,河南大学,2014-2018,主持。
(5)金银花等2种中药饮片标准化建设,国家中医药管理局中药标准化项目,国中医药办科技函[2016]154号,2016-2018,245万,参与人。
代表性论著(Publications)
1)期刊论文(Journal Articles) :
[1]Yantong Wu, Shasha Li, Jinjin Liu, Xiping Liu, Weimin Rua, Jengwei Lu, Yong Liu, Tom Lawson, Olga Shimoni, David Lovejoy, Adam K. Walker, Yue Cong*,Bingyang Shi. Stilbenes from Veratrum maackii Regel. protect against ethanol-induced DNA damage in mouse cerebellum and cerebral cortex. ACS Chemical Neuroscience, 2018, DOI: 10.1021/acschemneuro.8b00006
[2] Yue Cong, Bingyang Shi, Yiqing Lu, Shihui Wen, Roger Chung, Dayong Jin. One-step Conjugation of Glycyrrhetinic Acid to Cationic Polymers for High-performance Gene Delivery to Cultured Liver Cell. Scientific Reports, 2016, 6:1-11
[3] Yue Cong, Jun-Li Zhang, Sha-Sha Li, Shan Shen, Jiang-Ying Wang, Zong-Wei Cai. Pharmacokinetics and metabolism study of veratramine in mice after oral administration by using LC–MS/MS. Biomedical Chromatography, 2016, 30:1515-1522
[4] Yue Cong, Hualan Zhu, Qingchun Zhang, Lin Li, Haiyan L, Xianyou Wang, Jinggong Guo, Steroidal Alkaloids from Veratrum maackii Regel with Genotoxicity on Brain-Cell DNA in Mice, Helvetica Chimica Acta, 2015, 98(4) :539-545.
[5] Yue Cong, Jinggong Guo, Zhi Tang, Shuhai Lin, Qingchun Zhang, Jing Li, Zongwei Cai, Metabolism Study of Veratramine Associated with Neurotoxicity by Using HPLC–MSn, J Chromatogr Sci, 2015, 53 (7): 1092-1099.
[6] Yue Cong, Jing Li, Qingchun Zhang, Jing-Gong Guo, Shasha Li, Steroidal alkaloids from Veratrum dahuricum (TURCZ.) LOES. f. with genotoxicity on brain cell DNA in mice, Helvetica Chimica Acta, 2015, 98: 85-91.
[7] Yue Cong, Jinggong Guo, Zhi Tang, Qing-Chun Zhang, Zongwei Cai, Identification of in vitro and in vivo metabolites of 12β- hydroxylveratroylzygadenine associated with neurotoxicity by using HPLC- MS/MS. Chinese Chemical Letters, 2014, 25(8):1107-1111.
[8] Yue Cong, JingGong Guo, Jing Liu, Two new chemical constituents of Veratrum dahuricum (Turcz.) Loes. f., Helvetica Chimica Acta, 2013, 96(2):345-349.
[9] 郭敬功,李林,刘迎滑,王江英,李沙沙,沈姗,魏晓利,丛悦,王天晓.12β-羟基藜芦酰棋盘花胺对小鼠小脑和大脑皮层组织DNA损伤的影响. 中成药, 2016(8): 1668-1672.
[10] 郭敬功, 陈寅生, 李静, 王天晓, 李沙沙, 丛悦. 兴安藜芦中一个新橙酮苷. 药学学报, 2015, 50 (3): 337−339.
[11] 李沙沙,王江英,沈姗,武彦彤,刘习平,郭敬功,丛悦.12β-羟基藜芦酰棋盘花胺在小鼠体内的代谢研究. 中成药, 2017, 39(5), 1078-1081.
论著(Books):
[1] 丛悦副主编,实用天然药物化学,中国医药科技出版社, 2009.
[2] 丛悦参编,现代方剂新解,中国医药科技出版社,2011.