Yan Xi, an associate professor and master's supervisor at the School of Basic Medical Sciences, Henan University, is a faculty member in the Department of Pathology. My research primarily focuses on nano-oncology and cancer epigenetics, with a particular emphasis on the application and fundamental research of single-molecule super-resolution imaging technology for tumor biomarkers in clinical targeted cancer therapy. I have published five SCI papers, including in prominent nanobiology journals such as Nanoscale, and hold one national invention patent.
Principal Investigator, "Application of Single-Molecule Super-Resolution In Situ Imaging Technology in ADC Targeted Therapy for AML," Key Scientific Research Project of Henan Higher Education Institutions (Project No. 22A320031).
Principal Investigator, "Molecular Mechanism and Application of Autophagy-Related Protein ATG5 in Regulating Embryonic Stem Cell Differentiation," Henan Province Science and Technology Research Project (Project No. 2421023103920)
Sheng Li, Jin Sun, Bo-Wen Zhang, Lu Yang, Ying-Cui Wan, Bei-Bei Chen, Nan Xu, Qian-Ru Xu, Juan Fan, Jia-Ni Shang, Rui Li, Chen-Ge Yu, Yan Xi, Su Chen. ATG5 attenuates inflammatory signaling in mouse embryonic stem cells to control differentiation. Dev Cell, 2024,59 (7): 882-897.
Yan Xi, Dianbing Wang, Tingting Wang, Lin Huang, Xian-En Zhang. Quantitative profiling of CD13 on single acute myeloid leukemia cells by super-resolution imaging and its implication in targeted drug susceptibility assessment. Nanoscale, 2019, 11 (4): 1737-1744.(Awarded First Prize in the Youth Forum of the Second National High-End Forum on Biosensing, Biochips, and Nanobiotechnology)
Yan Xi, Junshi Zhang, et al. "Stereological Study on the Effects of Prenatal Alcohol Exposure on Synapses in the Visual Cortex of Offspring Rats." Acta Pharmaceutica Sinica, 2010, 45(6): 705-711. (in Chinese)(Awarded First Prize in the 2011 Natural Science Outstanding Paper Award of Henan Province).